Testosterone Deficiency
Testosterone deficiency or TD is exactly what it sounds like, a low amount of testostrone hormone in the body. TD increases with age, but can occur do to lifestyle choices such as steroid use as well. Testosterone levels decrease nearly 0.4% to 2% each year after the age of 30. Approximately 20-40% of men 45 years old or older show symptoms of low serum testosterone levels. Unfortunately, due to the variety of symptoms associated with TD, diagnosing and treating the hormone imbalance can be difficult. There are several reasons for the decline in testosterone including failure of the testes to produce testosterone, dysfunction of the HPG axis or androgen target tissue, medication or illness Since there are many causes, this lead to multiple classifications of TD. Primary hypogonadism is the most common form of TD. Primary hypogonadism, also known as hypergonadotropic hypogonadism, is an inability to produce testosterone or sperm in the presence of high concentrations of gonadotropins. Causes of primary hypogonadism include infection, medication side effects, toxins, testicular atrophy or testicular removal due to trauma. Secondary hypogonadism, or hypogonadotropic hypogonadism is caused by an alteration in the HPG axis, typically due to pituitary dysfunction or GNRH deficiency. This leads to a reduced level of FSH and LH production—hormones that stimulate sperm production and testosterone release.